BEGIN:VCALENDAR VERSION:2.0 PRODID:-//www.barthsyndrome.org//NONSGML kigkonsult.se iCalcreator 2.30.10/ / CALSCALE:GREGORIAN METHOD:PUBLISH UID:51604db0-c186-4fc5-91e9-48898ec5f223 X-WR-CALDESC:Over the past decade\, advances in early detection and diagnos is have begun to reveal the vast complexity of the primary etiologies that drive pathogenic cardiac remodeling and result in end-stage heart disease \; an enduring health burden in the United States and throughout the world . While current treatments focus on the late stages of disease\, where mor phology\, function and outcomes are often highly similar\, there is growin g evidence that improving patient care and management will require couplin g early diagnoses to specific\, targeted therapies that alter the natural history of these progressive and often devastating disorders. The developm ent of these targeted therapies will require new ideas\, new methodologies and new collaborations between basic and clinical scientists from dispara te fields of cardiovascular research.\n\nThe Gordon Research Conference (G RC) on Cardiac Regulatory Mechanisms was initiated in 1982 and has been at tended by multiple generations of leading scientists in the cardiovascular field every other year since. It is the premier conference centered on th e fundamental\, basic mechanisms that control normal cardiac function and how these systems are precisely altered in the context of pathogenic proce sses\, resulting in a broad range of cardiovascular disease states. The 20 20 GRC and its associated Gordon Research Seminar (GRS) for early career s cientists will focus on how the discovery of fundamental molecular process es can be leveraged for therapeutic intervention using approaches that enc ompass multiple levels of experimental resolution\, hence the the stated g oal to move the field towards the development of 'targeted therapies'. The subjects included in the program cover the latest advances in understandi ng cardiac function/dysfunction in the areas of heart failure\, inflammati on\, post-chemotherapy\, calcium regulation\, metabolic regulation and myo cellular structural dynamics.\n\nChairs\nJil Tardiff and Christoph Maack X-WR-RELCALID:0ff4613eb9741ecf6ed92e4d7ddb1d08 X-WR-TIMEZONE:America/New_York BEGIN:VTIMEZONE TZID:America/New_York BEGIN:STANDARD TZNAME:EST DTSTART:20191103T020000 TZOFFSETFROM:-0400 TZOFFSETTO:-0500 RDATE:20201101T020000 RDATE:20211107T020000 END:STANDARD BEGIN:DAYLIGHT TZNAME:EDT DTSTART:20200308T020000 TZOFFSETFROM:-0500 TZOFFSETTO:-0400 RDATE:20210314T020000 END:DAYLIGHT END:VTIMEZONE BEGIN:VEVENT UID:7c33e9fd-add7-4740-a1f5-b302ff997672 DTSTAMP:20260428T192312Z DESCRIPTION:Over the past decade\, advances in early detection and diagnosi s have begun to reveal the vast complexity of the primary etiologies that drive pathogenic cardiac remodeling and result in end-stage heart disease\ ; an enduring health burden in the United States and throughout the world. While current treatments focus on the late stages of disease\, where morp hology\, function and outcomes are often highly similar\, there is growing evidence that improving patient care and management will require coupling early diagnoses to specific\, targeted therapies that alter the natural h istory of these progressive and often devastating disorders. The developme nt of these targeted therapies will require new ideas\, new methodologies and new collaborations between basic and clinical scientists from disparat e fields of cardiovascular research.\n\nThe Gordon Research Conference (GR C) on Cardiac Regulatory Mechanisms was initiated in 1982 and has been att ended by multiple generations of leading scientists in the cardiovascular field every other year since. It is the premier conference centered on the fundamental\, basic mechanisms that control normal cardiac function and h ow these systems are precisely altered in the context of pathogenic proces ses\, resulting in a broad range of cardiovascular disease states. The 202 0 GRC and its associated Gordon Research Seminar (GRS) for early career sc ientists will focus on how the discovery of fundamental molecular processe s can be leveraged for therapeutic intervention using approaches that enco mpass multiple levels of experimental resolution\, hence the the stated go al to move the field towards the development of 'targeted therapies'. The subjects included in the program cover the latest advances in understandin g cardiac function/dysfunction in the areas of heart failure\, inflammatio n\, post-chemotherapy\, calcium regulation\, metabolic regulation and myoc ellular structural dynamics.\n\nChairs\nJil Tardiff and Christoph Maack DTSTART;TZID=America/New_York:20200621T000000 DTEND;TZID=America/New_York:20200626T235900 LOCATION:Colby-Sawyer College 541 Main Street New London\, NH\, US SUMMARY:POSTPONED: Cardiac Regulatory Mechanisms Gordon Research Conference Applying High Resolution Approaches to Complex Cardiac Disorders: Towards Targeted Therapies END:VEVENT END:VCALENDAR